Patent ductus arteriosus: pathophysiology and management

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Intravenous Paracetamol and Patent Ductus Arteriosus Closure

Background: Standard medical treatments for patent ductus arteriosus (PDA) closure are, including indomethacin/ibuprofen and surgical ligation. Nowadays, a new strategy to close PDA is the use of paracetamol. The present study aimed to describe the use of intravenous (IV) paracetamol for PDA closure in neonates who present a contraindication to ibuprofen or ibuprofen failure with no possibility...

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Management of patent ductus arteriosus.

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Patent ductus arteriosus.

The diagnosis of patent ductus arteriosus is difficult when the classic continuous murmur is not present. In infancy, in the presence of cardiac decompensation and when the ductus approximates the aorta in size, the continuous murmur is frequently absent. A correct diagnosis may be important, however, for a large patent ductus arteriosus can cause serious difficulty. Early surgical treatment ma...

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Atypical Patent Ductus Arteriosus

IN OUR EXPERIENCE about 95 per cent of patent ducti have the typical machinery murmur, and present no problem in diagnosis. A continuous murmur maximal in the second to third left intercostal space usually means patent ductus arteriosus. Other sites usually indicate other lesions. The typical machinery murmur reflects a systolic and diastolic pressure gradient between the aorta and pulmonary ar...

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[Atypical patent ductus arteriosus].

IN OUR EXPERIENCE about 95 per cent of patent ducti have the typical machinery murmur, and present no problem in diagnosis. A continuous murmur maximal in the second to third left intercostal space usually means patent ductus arteriosus. Other sites usually indicate other lesions. The typical machinery murmur reflects a systolic and diastolic pressure gradient between the aorta and pulmonary ar...

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ژورنال

عنوان ژورنال: Journal of Perinatology

سال: 2006

ISSN: 0743-8346,1476-5543

DOI: 10.1038/sj.jp.7211465